In a previous blog post we mentioned that it is possible to use IDA Pro with PySide (Python + Qt) after applying some minor code patches to PySide.
For convenience purposes, we precompiled the PySide libraries that work with IDA Pro 6.0+ and Python 2.6/2.7. Below is a brief explanation on how to install and use those binaries.
Edit: 2012-06-29 updated links for IDA 6.3/Python 2.7